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Diseases, Conditions, Syndromes
Machine learning tool identifies rare, undiagnosed immune disorders through patients' electronic health records
Researchers say a machine learning tool can identify many patients with rare, undiagnosed diseases years earlier than current methods, potentially improving outcomes and reducing cost and morbidity. The findings, led by researchers ...
4 hours ago
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Genetics
Researcher discusses mechanism behind a birth defect affecting brain size
Nonsense-mediated RNA decay, or NMD, is an evolutionarily conserved molecular mechanism in which potentially defective messenger RNAs, or mRNAs (genetic material that instructs the body on how to make proteins), are degraded. ...
3 hours ago
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Medical research news
New study supports psilocybin's potential as an antidepressant
Psilocybin—the active ingredient in "magic" mushrooms—is a more effective treatment for symptoms of depression than controls, providing further support for its potential as an antidepressant, suggests a study published ...
2 hours ago
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Global study reveals stark differences between females and males in disease burden causes
Globally, there are substantial differences between females and males (aged 10 and older) when it comes to health, with limited progress in bridging these health gaps over the past 30 years, according to a new study examining ...
2 hours ago
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Unraveling the roles of non-coding DNA explains childhood cancer's resistance to chemotherapy
St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non-coding regions of the genome contributing to chemotherapy resistance in acute lymphoblastic leukemia (ALL). The results guided ...
5 hours ago
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New technique improves T cell-based immunotherapies for solid tumors
Scientists from Scripps Research have enhanced an existing immunotherapy by removing the sugar coating surrounding solid tumors—such as in melanoma, breast, and prostate cancer—so T cells can more effectively kill tumor ...
5 hours ago
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A sum greater than its parts: Time-restricted eating and high-intensity exercise work together to improve health
Combining time-restricted eating with high-intensity functional training may improve body composition and cardiometabolic parameters more than either alone, according to a study published May 1, 2024, in PLOS ONE by Ranya ...
6 hours ago
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Brain imaging study reveals connections critical to human consciousness
In a paper titled, "Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness," published in Science Translational Medicine, a group of researchers at Massachusetts General Hospital and ...
6 hours ago
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Experimental vaccine targets portions of the flu virus that don't change
Duke researchers have opened a new avenue in the attack against influenza viruses by creating a vaccine that encourages the immune system to target a portion of the virus surface that is less variable.
6 hours ago
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Study finds ChatGPT fails at heart risk assessment
Despite ChatGPT's reported ability to pass medical exams, new research indicates it would be unwise to rely on it for some health assessments, such as whether a patient with chest pain needs to be hospitalized.
7 hours ago
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Preclinical study finds novel stem cell therapy boosts neural repair after cardiac arrest
Researchers at the University of Maryland School of Medicine (UMSOM) have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model. The study led by Xiaofeng ...
7 hours ago
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With huge patient dataset, AI accurately predicts treatment outcomes
Scientists have designed a new artificial intelligence model that emulates randomized clinical trials to determine the treatment options most effective at preventing stroke in people with heart disease.
8 hours ago
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Study indicates that cancer patients gain important benefits from genome-matched treatments
In 2016, The Jackson Laboratory (JAX) launched the Maine Cancer Genomics Initiative (MCGI) to bring the latest progress in cancer care to rural Maine patients. Now, after successfully expanding access to genome tumor testing ...
4 hours ago
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Long-term follow-up reports key findings and clinical messages from largest study of women's health in the US
Researchers from the Brigham and colleagues report on the long-term follow-up of the largest study of women's health in the U.S., shedding light on the role of menopausal hormone therapy, calcium and vitamin D supplementation, ...
9 hours ago
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New mRNA cancer vaccine triggers fierce immune response to fight malignant brain tumor
In a first-ever human clinical trial of four adult patients, an mRNA cancer vaccine developed at the University of Florida quickly reprogrammed the immune system to attack glioblastoma, the most aggressive and lethal brain ...
9 hours ago
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First effective treatment found for spitting cobra snakebite
Scientists have discovered a new snakebite treatment to prevent the devastating tissue damage caused by African spitting cobra venom.
9 hours ago
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Study in rats helps scientists work out the effects of exercise at the cellular level
The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought. In a study on rats, a team of scientists from across the ...
9 hours ago
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Scientists say sleep resets brain connections—but only for first few hours
During sleep, the brain weakens the new connections between neurons that had been forged while awake—but only during the first half of a night's sleep, according to a new study in fish by UCL scientists.
9 hours ago
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Research on how dietary choline travels through the blood-brain barrier reveals pathway for treating brain disorders
A University of Queensland researcher has found molecular doorways that could be used to help deliver drugs into the brain to treat neurological disorders.
9 hours ago
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Scientists identify new brain circuit in mice that controls body's inflammatory reactions
The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in mice from researchers at Columbia's Zuckerman Institute.
9 hours ago
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